Browsing by Author "Durmus, N."
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Effects of fluoxetine and LY 365265 on tolerance to the analgesic effect of morphine in rats
Ozdemir, E.; Bagcivan, I.; Gursoy, S.; Altun, A.; Durmus, N. (AKADEMIAI KIADO ZRT, 2011)Morphine is widely used to treat chronic pain, however its utility is hindered by the development of tolerance to its analgesic effects. The aim of this study was to investigate effects of fluoxetine, a specific serotonin ... -
The effects of L type calcium channels on the electroencephalogram recordings in WAG/RIJ rat model of absence epilepsy
Durmus, N.; Kaya, T.; Gulturk, S.; Demir, T.; Parlak, M.; Altun, A. (VERDUCI PUBLISHER, 2013)BACKGROUND: Epilepsy is one of the most important central nervous system disorder and 1% of the total world population suffers from this disorder which require a chronic drug treatment. Most of the researchers suggested ... -
Soluble guanylyl cyclase activators increase the expression of tolerance to morphine analgesic effect
Durmus, N.; Bagcivan, I; Ozdemir, E.; Altun, A.; Gursoy, S. (COMENIUS UNIV, 2014)Objectives: It is aimed to investigate the effects of guanylyl cyclase activation and inhibition on acute morphine antinociception and the development of tolerance to its effect. Background: Nitric oxide-soluble guanylyl ...